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Category: npj Digital Medicine

Digital mental health interventions in Chinese: a scoping review

Digital mental health interventions in Chinese: a scoping review

December 12, 2025December 12, 2025npj Digital Medicine

Digital mental health interventions (DMHIs) are playing an increasingly important role in supporting mental healthcare. Despite their widespread adoption during and after the COVID-19 pandemic, there has been a lack of review focused on…

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Association of sleep patterns assessed by a smartphone application with work productivity loss among Japanese employees

Association of sleep patterns assessed by a smartphone application with work productivity loss among Japanese employees

December 11, 2025December 11, 2025npj Digital Medicine

Sleep disturbances are an underrecognized factor associated with reduced workplace productivity (“presenteeism”). Previous studies have largely relied on self-reported sleep data, limiting their scalability and accuracy. We investigated associations between smartphone-based sleep metrics and…

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A CFIR-guided qualitative study of digital health engagement among Black adults with type 2 diabetes

A CFIR-guided qualitative study of digital health engagement among Black adults with type 2 diabetes

December 11, 2025December 11, 2025npj Digital Medicine

Digital health tools such as remote patient monitoring (RPM) and digital health coaching (DHC) offer promising strategies for type 2 diabetes (T2D) management, yet little is known about how underserved Black adults experience these…

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AI learning for pediatric right ventricular assessment: development and validation across multiple centers

AI learning for pediatric right ventricular assessment: development and validation across multiple centers

December 9, 2025December 9, 2025npj Digital Medicine

Congenital and acquired heart disease affects approximately 1% of children worldwide, and right ventricular (RV) dysfunction is a common and complex manifestation in conditions such as congenital heart disease, pulmonary hypertension, and prematurity. Accurate…

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Explainable AI-driven precision clinical trial enrichment: demonstration of the NetraAI platform with a phase II depression trial

Explainable AI-driven precision clinical trial enrichment: demonstration of the NetraAI platform with a phase II depression trial

December 9, 2025December 9, 2025npj Digital Medicine

Clinical trial failures are frequently driven by patient heterogeneity and limited sample sizes that obscure treatment effects by diluting statistical power. We introduce NetraAI, a novel explainable artificial intelligence (AI) platform that integrates dynamical-systems…

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If a therapy bot walks like a duck and talks like a duck then it is a medically regulated duck

If a therapy bot walks like a duck and talks like a duck then it is a medically regulated duck

December 5, 2025December 6, 2025npj Digital Medicine

Large language models (LLMs) are increasingly used for mental health interactions, often mimicking therapeutic behaviour without regulatory oversight. Documented harms, including suicides, highlight the urgent need for stronger safeguards. This manuscript argues that LLMs…

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African digital health strategic plans analysis: key weaknesses in contextualization, intervention focus, and technological foresight

African digital health strategic plans analysis: key weaknesses in contextualization, intervention focus, and technological foresight

December 5, 2025December 6, 2025npj Digital Medicine

Digital health strategies are increasingly being adopted in Africa, but their consistency with best practice planning is poorly documented. 54 countries were screened; 48 had a plan in the Global Digital Health Monitor, and…

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Metabolomic characterization of frailty identifies subtype-specific management strategies

Metabolomic characterization of frailty identifies subtype-specific management strategies

December 5, 2025December 6, 2025npj Digital Medicine

The clinical application of the frailty phenotype and frailty index still has some limitations, and whether the classification of frailty based on metabolites is beneficial to the management of the frailty population remains unclear….

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The cost of explainability in artificial intelligence-enhanced electrocardiogram models

The cost of explainability in artificial intelligence-enhanced electrocardiogram models

December 5, 2025December 6, 2025npj Digital Medicine

Artificial intelligence-enhanced electrocardiogram (AI-ECG) models have shown outstanding performance in diagnostic and prognostic tasks, yet their black-box nature hampers clinical adoption. Meanwhile, a growing demand for explainable AI in medicine underscores the need for…

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Active components in digital health interventions for sleep among adolescents: a systematic review and meta-analysis of randomized controlled trials

Active components in digital health interventions for sleep among adolescents: a systematic review and meta-analysis of randomized controlled trials

December 4, 2025December 4, 2025npj Digital Medicine

Digital health interventions (DHIs) offer scalable, accessible approaches to promote healthy sleep in adolescents and to prevent or treat poor sleep and insomnia. Given the high prevalence of sleep problems and their bidirectional links…

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The most evolutionary change coming to hospital rooms of the future is that they will be in your own home. For certain acute conditions, the hospital room will come to you. You will be able to convalesce in the comfort of your own home by using portable technology and next-generation healthcare equipment. This will allow for high quality care to be rendered in a person's home by medical professionals both onsite and virtually.

Nick Patel

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