Chiesi Wins FDA Approval for First Drug to Treat Ultra-Rare Enzyme Deficiency

Chiesi Wins FDA Approval for First Drug to Treat Ultra-Rare Enzyme Deficiency

A Chiesi Farmaceutici drug for a rare enzyme deficiency is now approved by the FDA, making it the first U.S. treatment for a disorder that leads to a range of cognitive and muscle problems.
The regulatory decision announced late Thursday covers the treatment of children and adults who have alpha-mannosidosis (AM), a disease caused by a genetic mutation that leads to defective or inactive forms of an enzyme called alpha-D-mannosidase. Chiesi’s drug, velmanase alfa, is an engineered version of that enzyme. The privately held Italian company will market its new FDA-approved drug as Lamzede, the same name for the product in Europe,…

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From Telemedicine to Complete Virtual Care and Beyond

From Telemedicine to Complete Virtual Care and Beyond

Michael Gorton, CEO of Recuro HealthTelemedicine has helped improve the quality of life of patients in every corner of the world and has been successfully utilized to provide convenient care to people with limited or no access to health services. Today, worldwide digital interconnectivity is growing, enabling telehealth to advance health equity, bring access to care for underserved regions and meet the urgent, primary and behavioral healthcare needs of an exploding global population.It has been a remarkable journey for the innovators who pioneered telemedicine. Since its inception, digital health services began the transformation from traditional healthcare — a reactive, disease-focused model…

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Johns Hopkins AI models predict ICU delirium risk

Johns Hopkins AI models predict ICU delirium risk

Two dynamic analytics models developed at Johns Hopkins University predicted delirium-prone patients when tested on two datasets drawn from 100,000 stays at a Boston hospital’s intensive care unit, according to new research.WHY IT MATTERS
Delirium – sudden bouts of confusion, inattention, paranoia, agitation and hallucinations – can put patients at higher risk of prolonged hospitalization, future dementia and death. By forecasting delirium, alerted clinicians could apply countermeasures that can mitigate adverse outcomes, according to the premise of artificial intelligence research published in Anesthesiology. 
“For a lot of these physiological transitions, we think that there are early warning signs that may not be obvious…

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FBI disrupts Hive ransomware: Hospitals among those spared

FBI disrupts Hive ransomware: Hospitals among those spared

Beginning this past July, the Federal Bureau of Investigation – with the assistance of overseas law enforcement agencies from Canada to Lithuania and victimized asset operators across various sectors – seized the servers and websites of the Hive ransomware network, FBI Director Christopher Wray announced on Thursday. The disruption makes hospitals safer against high-impact ransomware attacks, says the American Hospital Association.
Hive networks seized
The U.S. Attorney General Merrick Garland said yesterday that on the evening of January 25, a months-long investigation led to the seizure of Hive’s websites and servers. 
The FBI first gained access to Hive’s computer networks, then captured its decryption keys and offered…

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Orlando Health to launch AI-driven hospital-at-home services

Orlando Health to launch AI-driven hospital-at-home services

Data from the new hospital-at-home platform will be accessible through Orlando Health’s Epic electronic health records through a multiyear agreement with the connected health and digital therapeutics company.WHY IT MATTERS
Orlando Health – a nonprofit health system with 18 hospitals and emergency rooms, with five in development, serving the southeastern United States – is expected to launch the new advanced remote patient monitoring capabilities in early 2023.
Adding a virtual provider network can improve patient outcomes, prevent hospital readmissions, accelerate drug development and close critical gaps in care, according to the Biofourmis announcement. 
The data-driven platform takes physiological signal data from patient sensors – like…

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