Personalized CAR-T Cell Therapy

Personalized CAR-T Cell Therapy

Researchers at the Harvard Wyss Institute and the Dana-Farber Cancer Institute have developed a new method to prepare chimeric antigen receptor-T cells (CAR-T cells) for leukemia patients that could result in more effective treatment. CAR-T cells start life as T cells that are isolated from cancer patients, are stimulated and primed to recognize and attack cancer cells, expanded in number, and then reintroduced to the cancer patient with the goal that the cells will destroy their cancer. However, the technique works better in certain patients, and the researchers behind this latest technique have realized that T-cells from cancer patients do […]…

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Electrochemical Sensor for Detailed SARS-CoV-2 Immunity Data

Electrochemical Sensor for Detailed SARS-CoV-2 Immunity Data

Researchers at the Harvard Wyss Institute have developed an electrochemical device, called the eRapid sensor, that can assist clinicians in quickly characterizing someone’s COVID-19 infection, including identifying the infecting viral variant and the nature of someone’s immunity to the virus in terms of whether it is vaccine-mediated or natural immunity. Monitoring these characteristics could help to personalize treatment for individuals and also provide data for drug development and inform government decisions on the best way to manage COVID-19 in the community. When antibodies from a blood sample bind within the device, it precipitates a biochemical cascade that affects the electrical […]…

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